3D spot detection using the Determinant of Hessian (DoH) and the detection of 3D minima.
This workflow detects spots in a 2D image by filtering the image by Laplacian of Gaussian (user defined radius) and detecting regional intensity minima (user defined noise tolerance).
Provides a selection of spatial, separable and customizable filters in 1D and 2D, with OpenCL implementation if supported.
